The Situation

Challenge

• A product in phase III development preparing to enter an established
   market

• A prelaunch, copromote alliance

• Pre-existing global publication plan with the need for US focus

CHC response

• Reinforce the unmet medical need through targeted publications

• Reinforce the scientific platform through comprehensive publications
   expressing preclinical, phase II, and phase III data

• Establish points of product differentiation

• Prepare the market for a product that may provide enhanced patient
   outcomes

• Establish a strategic partnership for coordinated domestic and
   international scientific communications

The Partnership

Results

• An ongoing 5⁺-year client relationship

• Anticipation of a new therapeutic option in an established market

• Relationships with leading domestic and international thought leaders

Tactics

• Use of a publications database

• Congress briefing packages

• Competitive intelligence activities

• An effective bibliography including

   • 11 primary manuscripts

   • 4 review manuscripts

   • 161 abstracts

   • 159 posters

   • 10 oral presentations

   • 25 slide kits